Protein Details: Aquaporin Z
Protein ID
ICDB_Pro_1167
Protein Name
Aquaporin Z
Gene Name
aqpZ; fjo22
Organism
Flavobacterium johnsoniae (Cytophaga johnsonae)
Length
79 amino acids
AlphaFoldDB
AF-Q7WVD3-F1-model_v4.pdb
Function
Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
Sequence
MKKLFAEFFGTYWLVFGGCGSAVFAAGYPTLGIGFAGVALAFGLTVLTMAYAVGHISGGHFNPAVSFGLWAGGRFSAKD
PDB Structures
Ligand Binding
Binding Site
SITE 19: "Involved in tetramerization or stability of the tetramer"; SITE 42: "Selectivity filter"